Skip to content



Breakthrough research throughout Mass General Brigham—including the Massachusetts General Hospital, Brigham and Women’s Hospital, McLean Hospital, and Spaulding Rehabilitation Network – is redefining how healthcare is delivered.  From neuroinformatic analysis of big data to cutting-edge gene-editing technology, the research in progress at Mass General Brigham is truly game-changing.

Mass General Brigham innovators are finding ways to prevent, halt, and defeat neurological diseases ranging from Alzheimer’s to multiple sclerosis.  For example, Rudy Tanzi, PhD, the Joseph P. and Rose F. Kennedy Professor of Child Neurology at MGH made worldwide headlines in 2014 with his “Alzheimer’s-in-a-dish” approach that replaces mouse models with a 3-D culture system. In addition to breakthroughs in Alzheimer’s disease, Mass General Brigham covers the vast spectrum of Neurological disorders from autism and depression to schizophrenia and everything in between.


In the News

Forgot Something Again? It’s Probably Just Normal Aging

January 8, 2016

Losing your ability to think and remember is pretty scary. We know the risk of dementia increases with age. But if you have memory lapses, you probably needn’t worry. There are pretty clear differences between signs of dementia and age-related memory loss. After age 50, it’s quite common to have trouble remembering the names of…

Harvard’s Kevin Staley honored with AES Research Recognition Award for Basic Science

January 8, 2016

The American Epilepsy Society (AES) announces that Kevin Staley, M.D., professor of child neurology and mental retardation at Harvard Medical School and chief of pediatric neurology at Massachusetts General Hospital, is being honored with the AES Research Recognition Award for Basic Science at the Society’s 69th annual meeting in Philadelphia. Staley and his team’s work…

Windows Into The Brain

June 1, 2015

New imaging technologies create new neuroscience diagnostic and therapeutic tools. Ultra-high resolution imaging tools like 7-Tesla MRI now allow researchers to glimpse the brain in extraordinary detail, opening the door to new diagnosis and treatment of neurological disorders. Two imaging advances in particular – focused ultrasound and neuroimaging diagnostics in neurodegenerative and psychiatric illnesses –…

CNS Breakthroughs

December 1, 2014

A look into some of the groundbreaking neurological breakthroughs from Mass General Brigham' hospitals that will be featured at the World Medical Innovation Forum. The World Medical Innovation Forum will highlight neurological breakthroughs from around the globe. Some of the most important ones are right here at the Mass General Brigham' hospitals. Surgical Fusion At…

Innovation is Standard at McLean

May 1, 2014

The unique history of innovation that sets McLean Hospital apart from most freestanding psychiatric hospitals. Freestanding psychiatric hospitals sometimes find their reputations entwined in a history of tried-and-true traditional intervention, with cutting-edge research taking a backseat. But at McLean Hospital a history of innovation sets the institution apart. “McLean is one of the first institutions…

Technology Profile: New Point-of-Care Diagnostic for Epilepsy

December 1, 2013

Utkan Demirci, PhD collaborated with neurologist Steven Schachter, MD, to design a disposable microfluidic chip that can immediately detect the levels of antiepileptic drugs based on a finger-prick sample of blood. People suffering from epilepsy have long been at a disadvantage when trying to optimize the effectiveness of their antiepileptic drugs (AEDs). To do so…