FIRST LOOK: Stratifying Exercise Dysfunction


Exercise dysfunction is highly prevalent across the global spectrum of medical diseases, and is a principal cause of morbidity and increased healthcare cost burden. Abnormalities in multiple organ systems often underlie exercise dysfunction. However, current methods for analyzing exercise test results often rely on a narrow subset of variables involving a single organ system. This…

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Understanding Why Exercise Works for Just About Everything


Centuries ago, the Greek physician Hippocrates noted that when the body is “unused and left idle, it becomes liable to disease, defective in growth, and ages quickly.” These observations—made without the benefit of the exhaustive medical research and detailed studies that we have today—are just as valid now as they were then. Exercise is a…

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