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111

Expanding the Pool of Organs for Transplant

Heart transplantation does not adequately address the magnitude and severity of advanced heart failure (HF), a global…

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FIRST LOOK: Novel Target Discovery Pipeline for Calcific Aortic Valve Disease

Aortic stenosis due to calcific aortic valve disease (CAVD) is the most prevalent valvular disorder and is…

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blog

FIRST LOOK: Novel Target Discovery Pipeline for Calcific Aortic Valve Disease

Aortic stenosis due to calcific aortic valve disease (CAVD) is the most prevalent valvular disorder and is…

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FIRST LOOK: Stratifying Exercise Dysfunction

Exercise dysfunction is highly prevalent across the global spectrum of medical diseases, and is a principal cause…

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Understanding Why Exercise Works for Just About Everything

Centuries ago, the Greek physician Hippocrates noted that when the body is “unused and left idle, it…

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FIRST LOOK: Harnessing Endogenous Mechanisms of Programmed Gene Expression for Therapeutic Benefit in Cardiometabolic Disorders

Proximal mechanisms for programmatic control of gene expression exist that underlie the complex, distinct and at times…

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FIRST LOOK: Harnessing Endogenous Mechanisms of Programmed Gene Expression for Therapeutic Benefit in Cardiometabolic Disorders

Proximal mechanisms for programmatic control of gene expression exist that underlie the complex, distinct and at times…

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FIRST LOOK: Signaling and Pulmonary Vascular Disease

Our laboratory has investigated the role of bone morphogenetic protein (BMP) and transforming growth factor β (TGF-β)…

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FIRST LOOK: Atrial Fibrillation: Causal Basis and Personalized Risk Assessment

Cardiac arrhythmias are a leading cause of morbidity and sudden death, and collectively constitute a substantial public…

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